Estrogen Hormone May Help Traumatic Brain Injuries

According to a recent article in Science Daily, more than 1.7 million people sustain a traumatic brain injury each year and approximately 2750,000 are hospitalized annually with traumatic brain injuries; leaving 85,000 with long-term disabilities and killing more than 50,000.  The numbers are so high that it isn’t surprising how critical it is to identify a way to limit inflammation and subsequent damage within the brain.  Car accidents and falls are responsible for more than 5 million people living with disabilities caused by traumatic brain injuries.

Assistant Professor of Surgery at the University of Texas Southwestern Medical Center in Dallas, Dr. Joshua Gatson, investigates biomarkers and novel therapies for traumatic brain injuries.  He has found some promise in reducing inflammation and cell death in the brain with the naturally occurring estrogen hormone, estrone. 

According to his newest study, conducted on male rats, estrone provides anti-inflammatory and antioxidant capabilities after traumatic brain injury.    In his study he compares 0.5 mg of estrone to a placebo, both given 30 minutes after the injury.  The study revealed that estrone is involved in promoting a brain-derived neurotrophic factor (BDNF), which promotes cell survival.  Gatson says: “BDNF, one of the main growth factors that regulates repair following injury, is actually increased following treatment with estrone after traumatic brain injury.  So if you give this drug shortly after injury, it is thought to increase repair mechanisms.”

The brain injury attorneys at Fisher Stark Cash, P.A. thank and recognize Dr. Gatson for his work with estrone to help persons with traumatic brain injuries.  As attorneys who work with and represent persons with brain injuries we are excited about this medical advance.  If you or a loved one has experienced a brain injury call the attorneys at Fisher Stark Cash, P.A. at 828.505.4300.

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